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Sildenafil is the medical name for the active ingredient in Viagra tablets. The patent for Viagra held by the drug company Pfizer expired in June Since then a number of UK licenced brands of sildenafil have become available from various pharmaceutical manufacturers. These companies often market sildenafil branded by their company names, e. Patients with a brand preference can request preferred brand after making an order with Dr Fox. It is more accurate to say Viagra is a brand of sildenafil, and that sildenafil is the generic name.

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What is sildenafil, and how does it work mechanism of action? Viagra sildenafil is an oral drug that is used for treating impotence or erectile disfunction, ED, the inability to attain or maintain a penile erection. It has been estimated that impotence affects million men worldwide. Over half of all men with impotence are thought to have some physical medical cause. The remainder are believed to have psychogenic causes of impotence. Medical causes of impotence include diabetes and circulatory, neurological, or urological conditions. Penile erection is caused by the engorgement of the penis with blood. This engorgement occurs when the blood vessels delivering blood to the penis increase the delivery of blood and the blood vessels carrying blood away from the penis decrease the removal of blood. Under normal conditions, sexual stimulation leads to the production and release of nitric oxide in the penis. Nitric oxide then activates the enzyme, guanylate cyclase, which causes the production of cyclic guanosine monophosphate cGMP.

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Common side effects include headaches, heartburn, and flushed skin. The primary indication of sildenafil is treatment of erectile dysfunction inability to sustain a satisfactory erection to complete intercourse. Sildenafil and other PDE5 inhibitors are used off-label to alleviate vasospasm and treat severe ischemia and ulcers in fingers and toes for people with secondary Raynaud's phenomenon ; these drugs have moderate efficacy for reducing the frequency and duration of vasospastic episodes. In July, the FDA found that sildenafil could lead to vision impairment in rare cases, and a number of studies have linked sildenafil use with non-arteritic anterior ischemic optic neuropathy. Contraindications include::

Use sildenafil exactly as directed by your doctor. Special patient instructions comes with sildenafil. If you are using the oral liquid, shake the bottle well for at least 10 seconds before measuring each dose. Wash the oral syringe after each use. does not endorse companies or products.

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Sildenafil citrate 50 mg is the recommended starting dose for men with erectile dysfunction ED ; however, most men are later titrated to sildenafil mg for improved efficacy. Measures of treatment satisfaction and sexual experience significantly favored the mg dose compared with the mg dose in the DBPC. There was no increase in adverse events with the higher cheapest kamagra anywhere. Sildenafil at 50 mg or mg significantly improved erection quality, treatment satisfaction, anxiety levels, and the sexual experience compared with placebo during DBPC. Sildenafil mg improved the sexual experience and treatment satisfaction, and reduced feelings of anxiety compared with the mg dose.

Generic Viagra, or sildenafil, is a standard treatment for erectile dysfunction. This article discusses generic Viagra, including how it works, how to use it, and where to get it. Sildenafil citrate, or simply sildenafil, is the active ingredient in the brand-name drug Viagra. Sildenafil is known as generic Viagra because it is not sold under the Viagra brand name. People take it in a dosage of 25, 50, or milligrams mg per day. Sildenafil is a phosphodiesterase type 5 PDE5 inhibitor — the standard treatment for erectile dysfunction.

Men with ED who had previously completed 1 of 4 double-blind trials with short-term open-label extension combined duration, 0. Adverse events that were serious or led to dosing changes or discontinuation temporary or permanent were recorded. Many of the participants mean age, 58 range, 27—82 years; mean ED duration, 4. Thus, the long-term safety and effectiveness of sildenafil can now be evaluated in men who have been taking the drug for several years. The efficacy, safety, and tolerability of sildenafil in the treatment of men with ED have been demonstrated in numerous studies of 1-year duration or less. For example, 1, men with ED completed 1 of 4 double-blind trials and continued with open-label sildenafil treatment in extension studies for a total treatment duration of approximately 1 year Morales et al ; Steers et al