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Nerve pain, also known as neuropathic pain or neuropathy, refers to painful sensations around the nerves. Scientists define nerve pain or neuropathy as any condition in which an individual has sustained damage to their nerves. This article looks at the main types of medications for neuropathy, discussing which have the most positive effects. It also considers what the science has to say about nonpharmacological treatments for this condition. Research suggests that the prevalence of peripheral neuropathy is about 2.

 

Anticonvulsants are first-line medications that help manage the symptoms of seizure disorders, such as epilepsy. One important mechanism of action involves the ion channels, which are cell components that regulate cell function by letting mineral ions in and out. A paper suggests that some anticonvulsants are among the most effective medications for neuropathic pain. These first-line neuropathy medications act on specific ion channels that traffic calcium ions.

 

They include gabapentin Neurontin and pregabalin Lyrica. Gabapentin can also lead to blurred vision, while pregabalin can cause weight gain. Scientists also consider some antidepressants to be a first-line treatment for neuropathic pain. The most effective antidepressants for neuropathic pain are tricyclic antidepressants TCAs and serotonin—noradrenaline reuptake inhibitors SNRIs. However, these medications can also produce side effects. Amitriptyline is a TCA that can help people manage nerve pain.

 

However, it can lead to a host of unwanted effects, including In rare cases, some people may have serious side effects after taking amitriptyline. A study demonstrated that duloxetine was more effective than venlafaxine in decreasing the symptoms of chemotherapy -induced peripheral neuropathy. People should speak with a doctor if they are experiencing side effects that are affecting their quality of life.

 

Experts consider certain opioids to be a second-line treatment option. Tramadol Ultram and tapentadol Nucynta are opioids that can help with neuropathic pain.

 

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