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Roche is the second-largest pharmaceutical company worldwide. Roche is one of the few companies increasing their dividend every year, for as the 32nd consecutive year. Founded in by Fritz Hoffmann-La Roche, the company was early on known for producing various vitamin preparations and derivatives. In it introduced the class of tranquilizers known as benzodiazepines with and Rohypnol being the best known members. It manufactures and sells several cancer drugs and is a leader in this field.

In, the first antidepressant, iproniazid, was accidentally created during an experiment while synthesizing isoniazid. Originally, it had been intended to create a more efficient drug at combatting Tuberculosis. Iproniazid, however, revealed to have its own benefits; some people felt it made them feel happier.

It was withdrawn from the market in the early s due to toxic side-effects. In, an accident at a chemical factory in Seveso, Italy, owned by a subsidiary of Roche, caused a large dioxin contamination; see Seveso disaster. That company dated from the late s, and was located in Burlington, North Carolina. That year Hoffmann-La Roche then merged it with all of its laboratories, and incorporated the merged company as Roche Biomedical Laboratories, Inc.

Roche has also produced various HIV tests and antiretroviral drugs. It bought the patents for the polymerase chain reaction PCR technique in Oseltamivir is considered to be the primary antiviral drug used to combat avian influenza, commonly known as the bird flu. Roche is the only drug company authorized to manufacture the drug, which was discovered by Gilead Sciences. On 13 April, Roche acquired Medingo Ltd. The property is in the process of remediation. Hoffmann-La Roche is strong in the field pharmaceuticals for cancer treatment, against virus diseases and for treatment of metabolic diseases.

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