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Isotretinoin capsules are a very effective treatment for severe acne spots. This medicine can have serious side effects, however, so it must be prescribed and supervised by a specialist doctor. Isotretinoin capsules are for teenagers and adults with severe acne. Do not give isotretinoin capsules to children under the age of 12 years or before puberty. If you have diabetes, talk to your doctor before beginning treatment with isotretinoin capsules.

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Acne is a disease of pilosebaceous units in the skin. It is thought to be caused by the interplay of four factors. Excessive sebum production isotretinoin pills price to sebaceous gland hyperplasia is the first abnormality to occur. This microenvironment encourages colonization of Propionibacterium acnes, which provokes an immune response through the production of numerous inflammatory mediators. Inflammation is further enhanced by follicular rupture and subsequent leakage of lipids, bacteria, and fatty acids into the dermis.